Clinical Research & Studies

Scientific evidence behind our natural dog supplements. Manufactured in Germany under strict GMP standards.

Important Notice: The research presented here is for informational purposes only. These statements have not been evaluated by the European Food Safety Authority (EFSA). Our products are Ergänzungsfuttermittel (feed supplements) and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your veterinarian before starting any supplement regimen. This complies with German Feed Regulation (FuttMV) and EU Regulation 767/2009.

Research on Our Key Ingredients

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Liquid Silica

Essential trace mineral for skeletal structures, skin and coat health, and metabolic processes in dogs.

Research Note: 15 peer-reviewed studies on silica supplementation in canines.

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Bacillus Subtilis

Probiotic strain recognized as "Bacterium of the Year 2023" by VAAM (German Association for General and Applied Microbiology).

Research Note: 15 studies on probiotic effects in canine health.

Research-Based Formulation

Our formula combines liquid silica with Bacillus subtilis, recognized as the "Bacterium of the Year 2023" by the Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM).

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Bacterium of the Year 2023
Bacillus Subtilis - VAAM Recognition

Liquid Silica Research Findings

Summary of research findings from 15 peer-reviewed studies on liquid silica in canine nutrition:

Joint Health Research

Studies explore silica's potential role in supporting normal cartilage function and joint health in dogs.

Multiple peer-reviewed sources (2015-2023)
Joint Support

Bone Health Research

Research explores silica's potential role in supporting normal bone formation processes and mineral balance.

Veterinary nutrition studies
Bone Health

Skin & Coat Health Research

Studies explore silica's potential contributions to supporting normal skin health and coat condition in dogs.

Companion animal nutrition research
Skin & Coat

Mineral Support Research

Research explores silica's role as a trace mineral that may support normal metabolic processes.

Nutritional veterinary studies
Mineral Support

Research Disclaimer: These summaries represent general research findings. Individual results may vary. Always consult with your veterinarian before starting any supplement regimen.

Bacillus Subtilis Research Findings

Summary of research findings from 15 studies on Bacillus subtilis - "Bacterium of the Year 2023" (VAAM):

Gut Health Research

Studies explore B. subtilis' potential role in supporting normal digestive function and microbiome balance in dogs.

Probiotic research studies
Gut Health

Immune System Research

Research explores B. subtilis' potential contributions to supporting normal immune function in canines.

Veterinary immunology studies
Immune Support

Gut-Brain Axis Research

Studies explore the connection between gut microbiota and behavioral health in dogs.

Microbiome-behavior research
Behavior

Overall Health Research

Long-term studies investigate B. subtilis supplementation effects on canine health and wellbeing.

Longitudinal veterinary studies
Overall Health

Research Disclaimer: These summaries represent general research findings. Our products are food supplements and are not intended to prevent, treat, or cure any disease.

Research on Mechanisms of Action

Based on German pharmaceutical research, four primary mechanisms of action have been identified for Bacillus subtilis:

1. Antimicrobial Properties

Research shows B. subtilis produces various antimicrobial compounds:

  • Ribosomal peptides
  • Non-ribosomal peptides
  • Non-peptide substances

Research Note:

Multiple antimicrobial substances have been identified in B. subtilis research, demonstrating broad-spectrum activity in laboratory studies.

2. Immune System Support

Research Areas:

  • Innate immunity support
  • Adaptive immunity enhancement
  • Mucosal barrier function
  • Vitamin synthesis support

Research Note:

Studies indicate B. subtilis may support various aspects of immune function through multiple pathways.

3. Intestinal Microbiome Support

Research Findings:

  • Support for beneficial bacteria
  • Microflora diversity enhancement
  • Intestinal environment optimization

Research Note:

Studies show B. subtilis may support a balanced intestinal microbiome through various mechanisms.

4. Digestive Enzyme Production

Enzyme Categories:

  • Carbohydrate-digesting enzymes
  • Fat-digesting enzymes
  • Protein-digesting enzymes
  • Fiber-digesting enzymes

Research Note:

B. subtilis produces various digestive enzymes that may support nutrient breakdown and utilization.

Important: These mechanisms are based on laboratory research. Our products are dietary supplements and are not intended to diagnose, treat, cure, or prevent any disease.

Canine Nutritional Science

Formulation guidance based on "The Complete Guide to Dog Nutrition" by Katrina Graue.

Evidence-Based Nutritional Approach

Core Nutritional Principles:

  • Species-appropriate nutrition for canines
  • Life stage-specific requirements
  • Bioavailability optimization
  • Individual nutritional needs

Supplement Integration:

  • Targeted nutritional support
  • Natural ingredient sourcing
  • Safety and efficacy focus
  • Quality manufacturing standards

Educational Resource: The Complete Guide to Dog Nutrition provides comprehensive information on canine dietary requirements, supplement use, and health optimization strategies.

Research Summary

Scientific Foundation

Liquid Silica Research:

  • 15 peer-reviewed studies on silica in canine nutrition
  • Research on joint, bone, and coat health applications
  • Studies on mineral bioavailability and absorption

Bacillus Subtilis Research:

  • 15 studies on probiotic mechanisms and effects
  • VAAM recognition as "Bacterium of the Year 2023"
  • German pharmaceutical research on mechanisms of action

Important Research Disclaimer:

The research summarized here represents scientific studies on individual ingredients. Our products are dietary supplements for dogs and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your veterinarian before starting any supplement regimen.

Quality Assurance & Testing

Laboratory Testing

  • Heavy Metal Analysis: Testing for lead, mercury, cadmium, and arsenic
  • Microbiological Testing: Screening for harmful bacteria and pathogens
  • Potency Verification: Confirming active ingredient concentrations
  • Purity Analysis: Ensuring no contaminants or adulterants

Certifications & Standards

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GMP Certified Manufacturing
Good Manufacturing Practices in Germany
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ISO 22000 Food Safety
International food safety management standards
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Third-Party Verified
Independent laboratory testing and verification
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Natural Product Certification
Verified natural and organic ingredients

Research Articles & Deep Dives

Questions About Our Research?

Our scientific team is available to answer questions about our studies, methodologies, and findings.